Project number: 2018-099
Project Status:
Budget expenditure: $81,800.00
Principal Investigator: Matthew A. Landos
Organisation: Future Fisheries Veterinary Service Pty Ltd (FFVS)
Project start/end date: 18 Dec 2018 - 29 Aug 2019


The need for approved ag-vet chemicals was demonstrated during the response to the outbreak of the exotic pathogen white spot syndrome virus (WSSV) in 2016. WSSV is one of a number of exotic pathogens that have caused severe economic impacts for prawn aquaculture internationally. Review of the response to WSSV highlighted the need to access a number of ag-vet chemicals for use in disease prevention and control programs that have been developed by Biosecurity Queensland and industry, in conjunction with overseas experts. This application has been prepared to provide funds to commence generating the data required to support applications to the APVMA, seeking approval for minor-use of the highest priority ag-vet chemicals trichlorfon, sodium/calcium hypochlorite; hydrogen peroxide, copper sulfate and benzylkonium chloride that is needed to control crustacean disease vectors in water and on equipment.

There is limited published data on trichlorfon efficacy to kill Tiger prawns (Penaeus monodon), despite a range of data on efficacy in other species.
The APFA completed Pre-application Assistance (PAA) from the APVMA for the use of trichlorfon to rapidly kill prawns and other crustacea in 2017. APVMA intially indicated that data to meet module 7.3 environmental fate and behaviour assessment and a module 8.1 efficacy assessment is required prior to lodgement of an application for the proposed trichlorfon use.
Subsequently APVMA requested an application to be lodged with a complete public realm data set to consider. This data needs to be sourced and assembled.
APVMA may request further data to be generated in response to the lodgement of the application which is proposed to be gathered under this project for trichlorfon, and potentially some of the other candidate chemicals.


1. Compile public domain data ready for submission to APVMA for trichlorfon MUP
2. Compile public domain data ready for submission to APVMA for hydrogen peroxide MUP
3. Compile data for copper sulfate, sodium and calcium hypochlorite and benzylkonium chloride to progress towards application-ready status
4. Collect field data to support trichlorfon use as advised by APVMA

Final report

ISBN: 978-1-64764-071-2
Authors: Matthew A. Landos Tony Charles Kim Hooper James Fensham Chun-han Lin
Final Report • 2020-01-01 • 1.94 MB


The project involved generation of chemical data packages through review and aggregation of public domain documents for each chemical (trichlorfon, hydrogen peroxide, sodium and calcium hypochlorite, copper sulphate and benzalkonium chloride). This facilitated identification of data gaps requiring further data generation and progress towards the point of APVMA minor use permit application submission. Collection of field-based data was performed to meet APVMA requirements to support use of trichlorfon under a MUP.
Review of available knowledge and public domain literature was performed for Trichlorfon, Hydrogen Peroxide and Calcium and Sodium Hypochlorite to allow completion of data packages and facilitate subsequent submission of minor-use permit (MUP) applications to the Australian Pesticides and Veterinary Medicines Authority (APVMA). Review of available knowledge and public domain literature was performed for Benzalkonium Chloride and Copper Sulphate to allow identification of additional data requirements needed to complete of minor-use permit (MUP) applications.
This project has assisted to progress of Australian prawn farms access to priority chemical products that can assist farm biosecurity, through a process that aims to ensure safe and efficacy use of chemical products on Australian prawn farms.

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