73 results

The effects of vitamins and feeding frequency on the extension of the colour shelf life and maintenance of flesh quality of fresh and frozen Southern Bluefin Tuna (Thunnus maccoyii) flesh

Project number: 2019-166
Project Status:
Completed
Budget expenditure: $244,271.00
Principal Investigator: Erin J. Bubner
Organisation: Flinders University
Project start/end date: 2 Apr 2020 - 2 May 2021
Contact:
FRDC

Need

Commercial in confidence. To know more about this project please contact FRDC.

Objectives

Commercial in confidence
Industry
PROJECT NUMBER • 2018-102
PROJECT STATUS:
COMPLETED

Understanding Ostreid herpesvirus type 1 risk: alternative hosts and in situ hybridisation

South Australia (SA) has a large edible oyster industry primarily growing Pacific oysters (Crassostrea gigas). The industry is regionally-based, an important employer and a substantial contributor to regional economies. Pacific oyster mortality syndrome (POMS) is a serious infectious disease of C....
ORGANISATION:
Flinders University
Industry
Environment
Industry
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PROJECT NUMBER • 2012-750
PROJECT STATUS:
COMPLETED

SCRC: RTG: Visit to the laboratory of Professor Douglas Tocher (Institute of Aquaculture, University of Stirling, Scotland) to undertake collaborative research into the lipid and polyunsaturated fatty acid (PUFA) metabolism of Southern Bluefin Tuna

The purpose of this grant was to undertake collaborative research into the lipid and polyunsaturated fatty acid (PUFA) metabolism of Southern Bluefin Tuna (SBT) using a SBT cell line that was recently produced. This project followed an international trend towards increasing fish oil replacement in...
ORGANISATION:
Flinders University
Blank
PROJECT NUMBER • 2012-716
PROJECT STATUS:
COMPLETED

SCRC: PhD Extension : RNA interference (RNAi) as a means to control Neoparamoeba perurans, the causative agent of amoebic gill disease (AGD). (Student: Paula Lima)

RNA interference has emerged as a powerful tool for rapid analysis of gene function in non-model organisms and has the potential to identify candidate targets for interventions against diseases of economic importance to aquaculture. The main purpose of the study was to use functional and comparative...
ORGANISATION:
Flinders University
Blank
PROJECT NUMBER • 2012-714
PROJECT STATUS:
COMPLETED

SCRC: PDRS: Use of next generation DNA technologies for revealing the genetic impact of fisheries restocking and ranching

Several initiatives by the Australian Seafood CRC’s Future Harvest theme involve some form of stocking or enhancement of fisheries. In Western Australia, populations of Roe’s Abalone (Haliotis roei) are currently being restocked after the occurrence of a catastrophic mortality event,...
ORGANISATION:
Flinders University
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SCRC: Developing efficient diagnostic tools for assessing resistance to viral infection in abalone and oysters

Project number: 2011-758
Project Status:
Completed
Budget expenditure: $0.00
Principal Investigator: Peter Speck
Organisation: Flinders University
Project start/end date: 14 Mar 2012 - 29 Jan 2014
Contact:
FRDC

Need

The molluscan fisheries and aquaculture industries in Australia are threatened by herpesviruses. AbHV caused mass mortalities on Victorian farms from 2005-07 and is endemic off Victorian and possibly Tasmanian coasts. Herpesviruses are known to reactivate under stress conditions, threatening future productivity in the abalone industry and limiting movement of broodstock. Recently, OsHV-1 has been detected in Pacific Oysters in NSW, where it caused mass mortality and threatens the entire Australian oyster industry.

Research in France, where OsHV-1 is endemic, indicates that it is possible to select for higher resistance to this virus in oysters (ie. there is a strong genetic effect on resistance). Work by CSIRO and NSWI&I confirms that resistance to OsHV-1 is under strong genetic control. Screening of resistance level in the context of survivors within selected families is now being incorporated as a component of CRC project 2009/743.

Because molluscs lack acquired immunity, they cannot be vaccinated. The only feasible way to counter the threat of these viruses is to identify and develop resistant populations. As part of our current CRC PhD project (2008/739), we have developed an assay for screening antiviral activity in abalone haemolymph. The next step is to identify antiviral agents in abalone and oysters so they can be used as efficient diagnostic tools for identifying virus-resistant stocks. Biological and chemical screening assays, using antiviral activity and antiviral agent respectively, will be applied to different genetic breeding lines of abalone and oysters. We need to know if these assays could be used to improve resistance and whether genetic improvement of other traits such as growth rate might be compromised. Genetic analysis will determine whether haemolymph antiviral activity is under genetic control, is positively correlated with survival after challenge, and whether there are any undesirable associated effects.

Final report

ISBN: 978-0-646-92340-6
Authors: Dr P Speck A/Prof. K Benkendorff and Dr N Robinson.
Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

Final Report • 2014-06-01 • 205.62 KB
2011-758-DLD.pdf

Summary

The project examined the genetic basis of antiviral resistance in oysters and abalone in response to the significant disease threats posed by oyster and abalone herpesviruses. Laboratory-based systems for the growth and assay of such viruses are problematic. The project undertook to measure the antiviral activity of different breeding lines of oysters and abalone using as a proxy measure the antiviral activity against the human herpesvirus HSV-1. We demonstrated that oysters and abalone have antiviral activity against HSV-1, and that this trait is heritable. We identified a hemolymph compound providing antiviral activity. Our analysis of the oyster genome identified what is likely to be a key role for the protein viperin in resistance to viral infection. The project has provided outstanding value in three important areas. First, in adding to the knowledge base directing mollusc breeding programs. Second, in enhancing knowledge of molluscan immunity to viral infections. Third, in building research and development capacity in the Australian seafood industry.

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