1. Identification and characterisation of species-specific antigenic determinants that are heat-stable components of the lipopolysaccharide (LPS) on pathogenic gram-negative bacteria.

2. Prepare a library of species and genus-specific monoclonal antibodies against the heat-stable LPS components of pathogenic gram-negative bacteria

3. Select appropriate hybridomas, that produce high affinity monoclonal antibodies, for transfer to strategic companies

4. Complete the testing of specific LPS fragments extracted from one Vibrio species to produce vaccine against all Vibrio pathogens

5. Use the same approach as in (4) to test the genus-specific protection afforded by similar LPS fragrments extracted from additional pathogens, particularly Aeromonas salmonicida

6. Develop and market commercial products for use rapid diagnoses and in research of infections of wild and cultured fish and shellfish