PROJECT NUMBER
•
1981-007
PROJECT STATUS:
COMPLETED
ORGANISATION:
University of Queensland (UQ)
16 results
PROJECT NUMBER
•
2007-226
PROJECT STATUS:
COMPLETED
ORGANISATION:
University of Queensland (UQ)
SPECIES
Investigations into the toxicology of pectenotoxin 2 seco acid and 7-epi pectenotoxin 2 seco acid to aid in a health risk assessment for the consumption of shellfish contaminated with these diarrhetic shellfish toxins in Australia
Project number:
2001-258
Project Status:
Completed
Budget expenditure:
$20,000.00
Principal Investigator:
Glen Shaw
Organisation:
University of Queensland (UQ)
Project start/end date:
28 Mar 2002
-
30 Mar 2003
Contact:
FRDC
The need for the research lies in the fact that no guideline values exist for pectenotoxins in shellfish. To produce these guidelines toxicological data need to be produced and currently there is a lack of knowledge of the PTX metabolism and mechanisms of toxicity. There is currently no oral toxicology data on the PTX2- seco acids and thus their inpact on human health cannot be assessed. There have been no published works of their metabolism in mammals or humans, and their chronic effects on health are unknown. The clinical symptoms are non-specific to DSP poisoning and it is believed that cases of bacterial poisoning and DSP are mis-diagnosed due to lack of toxicological information.
The presence of pectenotoxins can impose significant economic burden on the shellfish industry. Clear toxicological data on pectenotoxins will be used to undertake a risk assessment of pectenotoxins to enable the shellfish industry and regulators to make informed decisions about the withdrawal of product from sale or closure of farms in the presence of pectenotoxins in shellfish.
1. A comprehensive study has been undertaken in which the aims are to (i) develop a robust method for extraction, purification and quantification of pectenotoxins in shellfish, (ii) investigate the pathology caused by the pectenotoxins when ingested orally, (iii) investigate P450 metabolism of the purified PTXs with the use of microarray technology and (iv) conduct a health risk assessment for the consumption of seafood contaminated with pectenotoxins. This study will provide a greater understanding of the metabolism and mechanisms of toxicity for the PTXs and provide information useful in the clinical assessment of poisoned patients and also provide information to be used in the setting of guideline values for pectenotoxins in seafood.
Final report
PROJECT NUMBER
•
1982-033
PROJECT STATUS:
COMPLETED
ORGANISATION:
University of Queensland (UQ)
PROJECT NUMBER
•
1980-043
PROJECT STATUS:
COMPLETED
ORGANISATION:
University of Queensland (UQ)
TAGS
PROJECT NUMBER
•
1976-005
PROJECT STATUS:
COMPLETED
ORGANISATION:
University of Queensland (UQ)
TAGS
PROJECT NUMBER
•
1993-153
PROJECT STATUS:
COMPLETED
ORGANISATION:
University of Queensland (UQ)
PROJECT NUMBER
•
1981-020
PROJECT STATUS:
COMPLETED
Investigations into QX disease in oysters and other problems associated with marine parasites
This long running FIRTA grant supported a center in Australia for research, consultancy and training on parasites and diseases important to the fishing industry. The center was established by FIRTA in 1977. During the life of FIRC 1981-020 many industry problems were successfully...
ORGANISATION:
University of Queensland (UQ)
PROJECT NUMBER
•
1986-096
PROJECT STATUS:
COMPLETED
Diseases of prawns in aquaculture: to develop procedures to detect pathogens of prawns shipped interstate
This project found and described a baculovirus similar to Monodon Baculovirus (MBV) that was called Plebejus Baculovirus (PBV) as it was in eastern king prawns (Penaeus plebejus). It later found it in Australian cultured Penaeus monodon.
The project investigated other conditions, particularly...
ORGANISATION:
University of Queensland (UQ)
Taxonomy and ecology of Vibrionaceae associated with red spot disease of Queensland aestuarine fish
Project number:
1984-026
Project Status:
Completed
Budget expenditure:
$0.00
Organisation:
University of Queensland (UQ)
Project start/end date:
28 Dec 1986
-
31 Dec 1986
Contact:
FRDC
1. Confirm involvement of Vibrio anguillarum or a related species in red spot disease in Qld commercial estuarine fish.
2. Clarify classification & methods for identification of the pathogen. Determine means of dispersal & role of host stress.
3. Develop strategy to minimise losses
