40,399 results

Investigations into the toxicology of pectenotoxin 2 seco acid and 7-epi pectenotoxin 2 seco acid to aid in a health risk assessment for the consumption of shellfish contaminated with these diarrhetic shellfish toxins in Australia

Project number: 2001-258
Project Status:
Completed
Budget expenditure: $20,000.00
Principal Investigator: Glen Shaw
Organisation: University of Queensland (UQ)
Project start/end date: 28 Mar 2002 - 30 Mar 2003
Contact:
FRDC

Need

The need for the research lies in the fact that no guideline values exist for pectenotoxins in shellfish. To produce these guidelines toxicological data need to be produced and currently there is a lack of knowledge of the PTX metabolism and mechanisms of toxicity. There is currently no oral toxicology data on the PTX2- seco acids and thus their inpact on human health cannot be assessed. There have been no published works of their metabolism in mammals or humans, and their chronic effects on health are unknown. The clinical symptoms are non-specific to DSP poisoning and it is believed that cases of bacterial poisoning and DSP are mis-diagnosed due to lack of toxicological information.

The presence of pectenotoxins can impose significant economic burden on the shellfish industry. Clear toxicological data on pectenotoxins will be used to undertake a risk assessment of pectenotoxins to enable the shellfish industry and regulators to make informed decisions about the withdrawal of product from sale or closure of farms in the presence of pectenotoxins in shellfish.

Objectives

1. A comprehensive study has been undertaken in which the aims are to (i) develop a robust method for extraction, purification and quantification of pectenotoxins in shellfish, (ii) investigate the pathology caused by the pectenotoxins when ingested orally, (iii) investigate P450 metabolism of the purified PTXs with the use of microarray technology and (iv) conduct a health risk assessment for the consumption of seafood contaminated with pectenotoxins. This study will provide a greater understanding of the metabolism and mechanisms of toxicity for the PTXs and provide information useful in the clinical assessment of poisoned patients and also provide information to be used in the setting of guideline values for pectenotoxins in seafood.

Final report

Industry
PROJECT NUMBER • 2000-211
PROJECT STATUS:
COMPLETED

Rock Lobster Enhancement and Aquaculture Subprogram: investigation of tail fan damage in live-held adult rock lobsters

An earlier project on liveholding of adult southern rock lobster, RLEAS 98/305, demonstrated that adult SRL could survive, feed, moult and grow when held in sea cages or raceways and fed an artificial diet developed in RLEAS 98/303. The major obstacle identified to such an industry was that...
ORGANISATION:
University of Adelaide

Development of intensive commercial aquaculture production technology for Murray cod

Project number: 1999-328
Project Status:
Completed
Budget expenditure: $393,730.00
Principal Investigator: Brett Ingram
Organisation: Agriculture Victoria
Project start/end date: 25 Jul 1999 - 11 Jan 2005
Contact:
FRDC

Need

1. The Murray cod is highly valued and sought after as a table fish.

2. The current market relies on a small wild commercial fishery which provides limited quantities
of fish of highly variable quality on a seasonal basis.

3. A hatchery-based industry for fingerling production is already well established in Victoria
and NSW.

4. Methods are currently being developed by both industry and government (MAFRI) to
commercially produce market-size Murray cod in tanks and ponds with both natural and artificial
diets under a range of intensive/semi-intensive and ambient/controlled environment conditions.

5. A new market-driven R&D program designed to facilitate industry development of Murray cod
aquaculture is planned, which will involve strong government support and industry support and
participation.

6. Intensive commercial production and associated value-adding and co-operative marketing will
provide more consistent quality and supply of product, with the added advantage of being able
to target niche markets.

A vertically integrated Murray cod aquaculture industry is envisaged for Australia, with some elements, already in place. Key components include a conventional three tier Production component, viz. Hatchery, Nursery, Growout, tapping into a four tier market scenario, viz. juveniles (for recreational and conservation stock enhancement and as seed for nursery and/or growout operations; the latter ultimately for human consumption), sub-adults/advanced stockers (for sale to growout operations and also small numbers selected for genetically improved/domesticated broodfish), Table/plate size fish (for human consumption; includes both domestic and export, live and gilled and gutted/fillet consumption), and broodfish (small numbers of genetically improved stock for future domesticated commercial strains of juveniles specially selected for the growout market). Some Production levels may also undertake hatchery and/or nursery operations for their own and other industry needs as a fully self-contained, fully integrated business unit. The proposed R&D project will focus on three key tasks, viz genetics improvement, diet development and fish health, all of which are relevant to varying degrees to all production levels/markets of the developing industry. A schematic summary of the above is attached for information.

Specific industry needs for Murray cod R&D for the proposed project have been identified as a two part consultation process (see also Section B5), viz:

1. A workshop on 13 August, 1998, convened by MAFRI, involving relevant scientific, extension and management personnel from MAFRI, Deakin University, Victorian Institute for Animal Science and Fisheries Victoria, and some 30 delegates from industry from both Victoria and NSW (including both practising and proposed Murray cod farmers)(see copy of Workshop agenda attached). This meeting established a network of Murray cod farmers that would be interested in collaborating on a project, together with identifying and setting broad R&D priorities for future work. The initial FRDC Murray cod funding proposal was developed largely on the basis of this proposal.

2. A detailed questionnaire was faxed to a selection of existing and/or proposed Murray cod farmers in Victoria, SA and NSW, including the preliminary R&D consortium established at the September 1998 workshop, on 11 March, 1999 (see list attached). This questionnaire summarised an annotated list of six key R&D priorities as discussed at the September workshop and invited farmers to score the priorities in order of decreasing importance/significance/need etc (see copy attached). The results of the questionnaire have been collated and summarised (see copy attached), with the outcome being that three specific R&D priorities have been clearly identified by industry (accounting for 63% of the total vote). Accordingly, the present proposal has been revised to reflect the specific needs identified by industry through this consultation process (see revised Objectives, Methods, Budget etc). A schematic summary of the developing Murray cod aquaculture industry, identifying the areas in which the proposed R&D priorities/actions are relevant is attached.

In summary, the key needs are:
1. Fish health: Minimising stress from outbreaks and therapeutic treatments to maximise not only survival but longer term growth is critical. Disease induced checks to growth at key physiological development stages has profound impacts on future production. eg. up to 30% loss of suitable seed can occur during the weaning/immediate post-weaning phase due to fish weakened by infection; survival in fry ponds can be reduced from an average of 75% to as low as 5% due to disease outbreaks etc..
2. Genetic improvement: most broodstock currently in use for seedstock production is essentially selected from wild populations and/or first generation (F1) progeny randomly selected from hatchery fish. The breeding system is defined as an "open" system in which there is no/little effort to select hatchery progeny as future broodstock based on specific characteristics suitable for specific markets. Indeed, to date considerable effort has been extended to ensure genetic integrity remains intact for enhancement of wild populations by maximising/randomising genetic resources. Selection for improved growout performance at the same time as protecting wild genetic material is the imperative.
3. Diet development: established feed regimes and associated diets currently in use are based largely on production of seed for enhancement and rely heavily on natural food production. Increased production through intensification requires higher energy, more efficient feeds and feed practices. Artificial diets currently in use for this purpose are largely adapted from existing salmonid, barramundi and silver perch diets, and are not species specific formulated. Consequent problems include sub optimal FCR's and developmental problems such as lipidosis.

Objectives

1. To develop and evaluate best practice husbandry, nutrition and fish health for commercial production of Murray cod under extensive pond-based hatchery, and intensive tank-based growout conditions.
2. To develop and implement an appropriate extension and associated market strategy to ensure effective and efficient transfer of research outcomes and associated protocols and technologies to industry.

Final report

ISBN: 0-86905-817-7
Author: Brett Ingram
Industry
Environment
PROJECT NUMBER • 1981-020
PROJECT STATUS:
COMPLETED

Investigations into QX disease in oysters and other problems associated with marine parasites

This long running FIRTA grant supported a center in Australia for research, consultancy and training on parasites and diseases important to the fishing industry. The center was established by FIRTA in 1977. During the life of FIRC 1981-020 many industry problems were successfully...
ORGANISATION:
University of Queensland (UQ)
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