A health promotion program incorporating fish for withdrawal of antihypertensive drugs in overweight hypertensives
Project number:
2002-242
Project Status:
Completed
Budget expenditure:
$103,637.00
Principal Investigator:
Lawrence Beilin
Organisation:
University of Western Australia (UWA)
Project start/end date:
13 Apr 2002
-
15 Jun 2005
Contact:
FRDC
The study will demonstrate the extent to which a health promotion program incorporating dietary fish meals, as well as weight control and increased physical activity, compares with usual care alone. The study is designed to reduce blood pressure and drug requirements in the longer term and minimise cardiovascular risk in overweight hypertensive patients. We will use ambulatory blood pressures as criteria for both inclusion and endpoints decisions and will assess quality of life and the cost-benefit in relation to lifestyle changes and overall cardiovascular risk. The results should have important implications for public health given the high prevalence of hypertensive cardiovascular disease.
0. To investigate whether, compared with a usual care group, a health promotion program incorporating increased fish consumption and improved dietary habits, as well as weight control and physical activity, will enhance blood pressure control, enabling antihypertensive therapy to be withdrawn for at least a year.
1. To investigate whether, compared with a usual care group, a health promotion program incorporating increased fish consumption and improved dietary habits, as well as weight control and physical activity, will lead to sustained improvements in cardiovascular risk profile in terms of lipids, glucose tolerance and blood platelet and endothelial activation.
